ProQ3D: improved model quality assessments using deep learning

نویسندگان
چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ProQ3D: improved model quality assessments using deep learning

Summary Protein quality assessment is a long-standing problem in bioinformatics. For more than a decade we have developed state-of-art predictors by carefully selecting and optimising inputs to a machine learning method. The correlation has increased from 0.60 in ProQ to 0.81 in ProQ2 and 0.85 in ProQ3 mainly by adding a large set of carefully tuned descriptions of a protein. Here, we show that...

متن کامل

ProQ3: Improved model quality assessments using Rosetta energy terms

Quality assessment of protein models using no other information than the structure of the model itself has been shown to be useful for structure prediction. Here, we introduce two novel methods, ProQRosFA and ProQRosCen, inspired by the state-of-art method ProQ2, but using a completely different description of a protein model. ProQ2 uses contacts and other features calculated from a model, whil...

متن کامل

Melanoma detection with a deep learning model

Background: Skin cancer is one of the most common forms of cancer in the world and melanoma is the deadliest type of skin cancer. Both melanoma and melanocytic nevi begin in melanocytes (cells that produce melanin). However, melanocytic nevi are benign whereas melanoma is malignant. This work proposes a deep learning model for classification of these two lesions.    Methods: In this analytic s...

متن کامل

Improved GQ-CNN: Deep Learning Model for Planning Robust Grasps

Recent developments in the field of robot grasping have shown great improvements in the grasp success rates when dealing with unknown objects. In this work we improve on one of the most promising approaches, the Grasp Quality Convolutional Neural Network (GQ-CNN) trained on the DexNet 2.0 dataset [15].We propose a new architecture for the GQ-CNN and describe practical improvements that increase...

متن کامل

Learning Face Image Quality from Human Assessments

Face image quality can be defined as a measure of the utility of a face image to automatic face recognition. In this work, we propose (and compare) two methods for learning face image quality based on target face quality values from (i) human assessments of face image quality (matcher-independent), and (ii) quality values computed from similarity scores (matcherdependent). A support vector regr...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Bioinformatics

سال: 2017

ISSN: 1367-4803,1460-2059

DOI: 10.1093/bioinformatics/btw819